EZ Cap Mouse CD252(OX40L) mRNA (m1Ψ, HA tag)

EZ Cap Mouse CD252(OX40L) mRNA (m1Ψ, HA tag)

Author: ApexBio

shortsummary:

Mouse CD252 mRNA with Cap 1 structure and HA tag sequence, modified by N1-Methylpseudo-UTP (m1Ψ), providing higher transcription efficiency and suppressing RNA-mediated innate immune activation.

2089251-47-6

DeliveryTime:

In stock

Yield RNA

ShippingType:

Dry ice

description:

CD252, also known as OX40 ligand (OX40L), is an important cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is mainly expressed on the surface of activated antigen-presenting cells such as dendritic cells, B cells and macrophages. CD252 performs its biological function by binding to the OX40 (CD134) receptor. The CD252-OX40 signaling pathway plays a key role in promoting T cell proliferation, survival and effector function, especially in regulating immune response, maintaining immune tolerance and anti-tumor immunity. In addition, CD252 is involved in the pathological processes of autoimmune diseases and chronic inflammation. Therefore, CD252 and its signaling pathway have become a hot spot in immunotherapy research, especially in cancer immunotherapy and autoimmune disease treatment.

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APExBIO Technology LLC is a premier provider of Small Molecule Inhibitors/Activators, Compound Libraries, Peptides, Assay Kits, Fluorescent Labels, Enzymes, Modified Nucleotides, mRNA synthesis and various tools for Molecular Biology. We carry a broad product line in over 25859 different research areas such as cancer, immunology, neurosciences, apoptosis and epigenetics etc. Based in USA (Houston, Texas), we have been serving the needs of customers across the world.